Target Medicals is a private biotech company with a substantial commercialisation potential of proprietary achievements in cytochrome P450s research.
Discovery and development of first-in-class therapeutics for subsequent co-development or out-licensing.
• Design, expression and purification of cytochrome P450s ready for use in any applications;
• Cytochrome P450-based functional assays (activity in the reconstituted system, products identification) and assay development;
• HTS assay for screening cytochrome P450s ligands;
• Crystallization of cytochrome P450s in complex with ligands;
• Recombinant antibodies development for conformational and linear epitopes of cytochrome P450s.
RECOMBINANT PROTEIN SUPPLY
We are able to supply a highly purified recombinant human and pathogenic cytochrome P450s (CYPs), their redox partners and modulators (P450-reductase, adrenodoxin reductase, adrenodoxin, cytochrome b5). List of CYPs will provided upon request.
Part of out purified cytochromes P450 portfolio is also available through Sigma Aldrich Inc. (http://www.sigmaaldrich.com/life-science/biochemicals/biochemical-products.html?TablePage=118899716).